Nicotinamide Riboside—Your New Chance for Success

Nicotinamide Riboside—Your New Chance for Success

Posted by Ada Brown on Jun 15, 2016 2:44 am

Nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in redox activities in the mitochondrial electron transport chain, has been identified as a key regulator of the lifespan-extending effects, and the activation of NAD expression has been linked with a decrease in beta-amyloid (Ab) toxicity in Alzheimer’s disease (AD).
 
Nicotinamide riboside (NR) is a NAD precursor, it promotes peroxisome proliferator- activated receptor-g coactivator 1 (PGC)-1α expression in the brain. Evidence has shown that PGC-1α is a crucial regulator of Ab generation because it affects b-secretase (BACE1) degradation.
 
NR naturally occurs in yeast, bacteria, and mammals, and is present in milk and beer. It is metabolized by two metabolic pathways. The first is a degradative pathway that produces nicotinamide. The second pathway involves NR kinases. Through those pathways, NR is converted to NAD+.
 

Re: Nicotinamide Riboside—Your New Chance for Success

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Re: Nicotinamide Riboside—Your New Chance for Success

Posted by Yasmin Hussain on Jun 17, 2020 11:32 am

From what I know, nicotinamide riboside is an alternative form of vitamin B3. It’s promoted as an anti-aging supplement because it boosts your body’s levels of NAD+.

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